Authors:
Ceaciru Cristina, Gonta Maria, Gutu Iacob, Ceaciru Mihail, Lupascu Tudor
Ceaciru Cristina, Gonta Maria, Gutu Iacob, Ceaciru Mihail, Lupascu Tudor
Conference: International Symposium “The Environment and the Industry”
Date: 26-27 September 2019
Location: Bucharest, Romania
Published: 2019
Keywords:
Chitosan
Functionalization
Quercetine
Thiosemicarbazone
Abstract:
Cancer is a major health problem and is the second leading cause of death in the world. DNA oxidation can cause mutations and can therefore play an important role in the initiation and progression of carcinogenesis.Various antioxidants can be used to inhibit the DNA oxidation process, which may in the first place protect the DNA and, secondly, inhibit the formation of N-nitrosamines, which in turn ~ 80% are carcinogenic substances. Natural polymers (chitosan) functionalized with polyphenols can be used to prolong these effects. Chitosan is a natural polymer that is abundant in nature. Due to its unique biological properties, chitosan is applied in many industries. Polyphenols are well known for their antioxidant properties, they are natural compounds with one or more phenolic groups. In this paper, the functionalization of chitosan with cvercitine was studied and the antioxidant properties of the obtained composite were determined.