05
Oct 2017
0

DOI:10.21698/simi.2017.0038
STUDY OF BACTERIA RESISTANCE MECHANISMS IN RESPONSE TO A STRESS INDUCED BY PHARMACEUTICALS COMPOUNDS

Pollution control and monitoring, Proceedings Book SIMI 2017, SIMI-2017 simiecoind

Authors:
Logan Marthe, Catalina Stoica, Laura Florentina Chiriac, Toma Galaon, Mihai Nita-Lazar
Conference: International Symposium “The Environment and the Industry”
Date: September 28-29, 2017
Location: Bucharest, Romania
Published: 2017
Keywords:
Biological adaptive markers
Pharmaceutical compounds
Gram-negative bacteria
Defense mechanisms

Abstract:

Three pharmaceutical compounds (Trimethoprim, Carbamazepine and Benzethonium
chloride) were investigated to unveil possible toxic effects on two bacterial strains
(Citrobacter freundii and Comamonas testosteroni). The pharmaceutical compounds
stress triggered a bacterial defence mechanism which was evaluated at transcriptional
and translational levels. In this study, potential bacterial biomarkers induced by the
pharmaceutical stress were unraveled.

[Read entire document here]